数据库简述：A pan-cancer analysis of synonymous mutations
数据库主要信息：SynMICdb aims to facilitate the study of synonymous mutations in cancer. These mutations alter the nucleotide sequence of the gene and the mRNA, but not the amino acid sequence of the respective protein. Synonymous mutations can change mRNA structure, stability, splicing, translation efficiency or impact cis-regulatory sequences. These mutations can be recurrent and conserved and mirror many aspects of cancer driving mutations.
University of Freiburg
Division of Cancer Research, Department of Thoracic Surgery, Medical Center, University of Freiburg, 79085 Freiburg, Germany
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