数据库简述：the Retroviral Tagged Cancer Gene Database
数据库主要信息：To manage multiple high-throughput insertional mutagenesis screening projects, we developed the Retroviral Tagged Cancer Gene Database (RTCGD). A sequence analysis pipeline determines the genomic position of each retroviral integration site cloned from a mouse tumor, the distance between it and the nearest candidate disease gene(s) and its orientation with respect to the candidate gene(s). The pipeline also identifies genomic regions that are targets of retroviral integration in more than one tumor (common integration sites, CISs) and are thus likely to encode a disease gene.
National Cancer Institute
Mouse Cancer Genetics Program, National Cancer Institute, Frederick, MD 21701, USA.
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