数据库名称:PDTD
数据库简述:
所属国家/地区:China
数据库主要信息:PDTD is a web-accessible protein database for in silico target identification. It currently contains >1100 protein entries with 3D structures presented in the Protein Data Bank. The data are extracted from the literatures and several online databases such as TTD, DrugBank and Thomson Pharma. The database covers diverse information of >830 known or potential drug targets, including protein and active sites structures in both PDB and mol2 formats, related diseases, biological functions as well as associated regulating (signaling) pathways. Each target is categorized by both nosology and biochemical function. PDTD supports keyword search function, such as PDB ID, target name, and disease name. Data set generated by PDTD can be viewed with the plug-in of molecular visualization tools and also can be downloaded freely. Remarkably, PDTD is specially designed for target identification. In conjunction with TarFisDock, PDTD can be used to identify binding proteins for small molecules. The results can be downloaded in the form of mol2 file with the binding pose of the probe compound and a list of potential binding targets according to their ranking scores.
建立年份:2008
联系信息:Contact information
University/Institution:
Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Address:
City:
Shanghai
Province/State:
Shanghai
Country/Region:
China
Contact name (PI/Team):
Gao Z
Contact email (PI/Helpdesk):
zhentg@mail.shcnc.ac.cn