数据库名称：PanDrugs
数据库简述：prioritizing cancer therapies using integrated individual multi-omics data
所属国家/地区：Spain
数据库主要信息：Here, we introduce PanDrugs2, a major upgrade of PanDrugs that, in addition to somatic variant analysis, supports a new integrated multi-omics analysis which simultaneously combines somatic and germline variants, copy number variation and gene expression data. Moreover, PanDrugs2 now considers cancer genetic dependencies to extend tumor vulnerabilities providing therapeutic options for untargetable genes. Importantly, a novel intuitive report to support clinical decision-making is generated. PanDrugs database has been updated, integrating 23 primary sources that support >74K drug-gene associations obtained from 4642 genes and 14 659 unique compounds. The database has also been reimplemented to allow semi-automatic updates to facilitate maintenance and release of future versions.
建立年份：2023
联系信息：Contact information
University/Institution:
Spanish National Cancer Research Centre
Address:
Bioinformatics Unit, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain
City:
Province/State:
Country/Region:
Spain
Contact name (PI/Team):
Fátima Al-Shahrour
Contact email (PI/Helpdesk):
falshahrour@cnio.es
