数据库简述：a database of extrachromosomal circular DNA profiles in human cancers
数据库主要信息：eccDNAdb is a database of extrachromosomal circular DNA profiles in human cancers, and it aims to acquire known and novel extrachromosomal circular DNAs (eccDNAs) in cancers by computational analysis of whole-genome sequencing data. It currently includes 1270 eccDNAs, which were identified in 480 samples (of 42 cancers) after analyzing a total number of 3395 tumor samples (of 57 cancers) including patient tissues, patient-derived xenografts, and cancer cell lines. A total number of 54,901 eccDNA genes were annotated and included in the database as well. With the integration of gene expression, clinical information and chromatin accessibility data, eccDNAdb enables users to easily determine the biological function and clinical relevance of eccDNAs in human cancers.
Sun Yat-Sen University
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