dbAMEPNI数据库介绍

数据库名称:dbAMEPNI

数据库简述:a database of alanine mutagenic effects for protein-nucleic acid interactions.

所属国家/地区:China

数据库主要信息:web-based and searchable database of alanine-scanning mutations and their effects on the binding affinity of protein-nucleic acid interactions. The molecular types of nucleic acids can be classified into five major categories: a hybrid of DNA/RNA, dsDNA (double-stranded DNA), ssRNA (single-stranded RNA), ssDNA (single-stranded DNA), and dsRNA (double-stranded RNA). dbAMEPNI is a manually curated, literature-derived database, focusing on the effects of single alanine-scanning mutations on the binding affinities of protein-nucleic acid interfaces. As of November 2017, it comprises a total of 859 alanine-scanning mutant residues with quantitative or qualitative data in the change on binding affinity (details shown in below), extracted from 217 protein-nucleic acids complexes with three dimensional structures, which are deposited in Protein Data Bank (PDB). The database not only provides a benchmark dataset for developing efficient computational methods to predict unknown hotspots (i.e., ΔΔG >= 2.0 kcal/mol) on protein-nucleic acid interfaces, but also will be benefit for studying the principal rules governing protein-nucleic acids interactions.

建立年份:2018

联系信息:Contact information

University/Institution:
Anhui University

Address:
Zhu, Xiaolei

School of Life Sciences
Anhui University
Building C of Science and Technology

111 Jiulong Road, Jingkai Qu

Hefei, Anhui 230601, China

Email:xlzhu_mdl@hotmail.com

City:
Hefei

Province/State:
Anhui

Country/Region:
China

Contact name (PI/Team):
Zhu, Xiaolei

Contact email (PI/Helpdesk):
xlzhu_mdl@hotmail.com

常见问题
  • 如何在体龙基因完成所需的检测项目 流程简述 :在线咨询 - 采样送检 - 付款检测 - 检测分析 - 报告结果
查看详情

相关内容

官方客服团队

为您解决烦忧 - 24小时在线 专业服务